Test

HME (Ehrlichia chaffeensis) PCR Whole Blood

$230.00

The polymerase chain reaction (PCR)-based diagnostic assays are highly specific to Ehrlichia chaffeensis (HME) DNAs. The combination of the following three steps imparts a very high specificity and sensitivity to the test:

1. Hybridization/selection
2. Amplification of Ehrlichia-specific DNA
3. Detection of Ehrlichia-specific amplified DNA fragments

Principle
The Ehrlichia chaffeensis (HME) PCR test detects E. chaffeensis ribosomal DNA (rDNA) fragments in patient samples. The rDNA fragments are hybrid-selected by probes, followed by PCR amplification of the selected fragments using specific primers. PCR products are then confirmed with E. chaffeensis-specific probes by southern blot assay.

Tube / Specimen Requirements
1 Full EDTA

CPT Code(s)
87798

Sample Report
View

Test Number 770 Categories , Tags , Stage of Disease

Any Stage of Disease

Test Methodology

PCR

Available in New York

Yes

• Enables accurate identification of biochemically unusual strains of pathogen.
• Facilitates much earlier detection of the microorganism because the assay is independent of the host’s immune response schedule.
Therefore, PCRs are useful for seronegative patients as well.
• Allows monitoring of the efficacy of an antibiotic regime.
• PCRs detect the DNA of the bacteria itself. Therefore, a positive result is definitive.

Positive: E. chaffeensis rDNA detected.

Negative: E. chaffeensis rDNA not detected.

  1. Ehrlichia test results should be interpreted in conjunction with other laboratory and clinical findings.
  2. Test results can only help the physician in confirming a clinical diagnosis.

GET STARTED TODAY!

The first step in getting tested with IGeneX is to order a collection kit. Choose between a Blood, Urine, or Miscellaneous kit.

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