• Indirect testing, and therefore useful when the pathogens are hiding or not active.
• Active infection may be indicated when either IgM only, IgM and IgG, or IgG (≥ 160) antibodies are present.
$160.00
The Ehrlichia chaffeensis (HME) IFA is designed to detect human IgG and IgM antibodies to HME antigens in human serum. For diagnostic purposes, HME IFA test results should be used in conjunction with other information available to the diagnosing physician.
The Ehrlichia IFA assay is a two-stage sandwich assay, based upon an antigen-antibody complex formation in the following steps:
Principle
Titers rise during the first two-to-four weeks of illness and decline over the next six-to-12 months. In patients with previously high titers, the presence of only IgG titer of less than 160 may indicate a resolving infection. If the IFA result is negative, but the clinical symptoms of HME infection are present, PCR testing is suggested. E. chaffeensis is carried by the same ticks that have also been known to cause Babesiosis, Bartonellosis and Lyme disease. Patients with positive titers should also be tested for other tick-borne diseases.
Tube / Specimen Requirements
1 SST/ minimum volume 0.5mL serum
CPT Code(s)
86666 x2
Sample Report
View
Early Disease, Late Disease
Test MethodologyIFA
Available in New YorkYes
• Indirect testing, and therefore useful when the pathogens are hiding or not active.
• Active infection may be indicated when either IgM only, IgM and IgG, or IgG (≥ 160) antibodies are present.
IgM
< 20 Negative
20 May or may not indicate active infection.
≥ 40 Indicates active infection.
IgG
< 40 Negative
≥ 40 to < 160 May or may not suggest active infection. In patients with previously high titers, such titers may indicate resolving infection.
≥ 160 Indicates active infection.
The first step in getting tested with IGeneX is to order a collection kit. Choose between a Blood, Urine, or Miscellaneous kit.
1.800.832.3200
For the most up to date and accurate information and articles about ticks and tick-borne diseases, please visit Tick Talk Resource.
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