• Detects specific T-cell responses soon after Bartonella infection, when antibodies to the organisms are not detectable or late in the disease when the levels of antibodies are very low.
• When combined with ImmunoBlot tests, provides information on the full spectrum of a patient’s immune response to infection and stage of disease.
• Especially useful for seronegative patients.
Positive: > 3 CFU
Negative: < 2 CFU
For diagnostic purposes, the IgXSpot test results should be used in conjunction with clinical symptoms and other evidence available to the diagnosing physician. If the test result is negative, testing with another method is recommended. Depending on the stage of the disease patients can have either humoral or cellular immune response to infection. Thus, it is advisable to perform Bartonella species ImmunoBlot IgM and IgG tests with IgXSpot test.