Test

Babesia FISH

$220.00

The Babesia FISH assay is designed for qualitative detection of ribosomal RNA of Babesia parasites directly in a blood smear. The test’s highest degree of specificity is provided by nucleic acid probes, which bind to RNA sequences of the Babesia. This test detects all species of Babesia.

Principle
The FISH assay is based on two fundamental principles: Hybridization directly on a thin blood smear with a fluorescein-labeled Babesia specific probe; identification of Babesia parasites on a blood smear by viewing with a fluorescent microscope. The FISH assay provides a significant increase in sensitivity and specificity over standard Giemsa-stained smears for the presence of intraerythrocytic parasites (piroplasts) in RBCs. The parasites exist as a ring and/or merozoite forms. A positive sample must show fluorescing rings in at least two RBCs. A negative sample must show no fluorescence within the RBCs.

Tube / Specimen Requirements
1 Full EDTA – do not freeze

CPT Code(s)
88365

Sample Report
View

Test Number 640 Categories , Tags , Test Methodology

FISH

Available in New York

Yes

• Detects active infection.
• Detects a broad range of species of Babesia.

Positive: Babesia specific rRNA detected. A positive sample must show fluorescing rings inside at least
two RBCs.

Negative: Babesia specific rRNA not detected. A negative sample must show no fluorescence within RBCs.

  • A single negative FISH test result does not exclude the possibility of Babesia infection.
  • Results should be interpreted in conjunction with other laboratory and clinical findings.

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The first step in getting tested with IGeneX is to order a collection kit. Choose between a Blood, Urine, or Miscellaneous kit.

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